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연구자 DB RESEARCHER DB

연구자 정보

  • 성명김영명
  • 소속의학과
  • 세부전공발달생화학
  • 연구분야혈관생물학, 신호전달, 면역생화학
기술 매칭을 원하시는 분은 아래 담당자로 연락주시기 바랍니다.
기술매칭 수요 접수 담당자 : 고경란 Tel : 033-250-6942 | E-mail : ko@kangwon.ac.kr

보유기술 (3건)

보유기술
순번 지재명권 등록년도
3 디히드록시페닐 유도체를 함유하는 혈관질환 예방 또는 치료용 약학적 조성물 2018
2 임신중독증의 예측 또는 진단을 위한 바이오마커로서의 miRNA-214-3p 및 miRNA-1290-3p 2021
1 염증 사이토카인에 의한 혈관내피전구세포의 기능 장애에서 NF-κB-의존적 miR-31-5p와 miR- 155-5p의 역할 및 이의 이용 2020

연구과제 (1건)

  • 2017년 한국연구재단(EZBARO) 암혈관 신생과 비정상화 분자조절 기전 규명을 통한 암 치료 원천기술 개발

논문/저서 (77건)

  • 2018년 혈관생물학, 신호전달, 면역생화학 Yonsei Medical Journal Arginase Inhibition Suppresses Native Low-Density Lipoprotein-Stimulated Vascular Smooth Muscle Cell Proliferation by NADPH Oxidase Inactivation
  • 2019년 혈관생물학, 신호전달, 면역생화학 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Antioxidant Properties of Fucoidan Alleviate Acceleration and Exacerbation of Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia in High-Fat Diet-Induced Obese Gerbils
  • 2019년 혈관생물학, 신호전달, 면역생화학 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Fate of Astrocytes in The Gerbil Hippocampus After Transient Global Cerebral Ischemia
  • 2019년 혈관생물학, 신호전달, 면역생화학 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Risperidone Treatment after Transient Ischemia Induces Hypothermia and Provides Neuroprotection in the Gerbil Hippocampus by Decreasing Oxidative Stress
  • 2021년 혈관생물학, 신호전달, 면역생화학 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Increased Calbindin D28k Expression via Long-Term Alternate-Day Fasting Does Not Protect against Ischemia-Reperfusion Injury: A Focus on Delayed Neuronal Death, Gliosis and Immunoglobulin G Leakage
  • 2021년 혈관생물학, 신호전달, 면역생화학 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Therapeutic Efficacy of a Novel Acetylated Tetrapeptide in Animal Models of Age-Related Macular Degeneration
  • 2021년 혈관생물학, 신호전달, 면역생화학 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES CD200 Change Is Involved in Neuronal Death in Gerbil Hippocampal CA1 Field Following Transient Forebrain Ischemia and Postischemic Treatment with Risperidone Displays Neuroprotection without CD200 Change
  • 2019년 혈관생물학, 신호전달, 면역생화학 MOLECULAR MEDICINE REPORTS Resveratrol is an arginase inhibitor contributing to vascular smooth muscle cell vasoconstriction via increasing cytosolic calcium
  • 2018년 혈관생물학, 신호전달, 면역생화학 MOLECULAR MEDICINE REPORTS Effects of chronic scopolamine treatment on cognitive impairment and neurofilament expression in the mouse hippocampus
  • 2020년 혈관생물학, 신호전달, 면역생화학 MOLECULAR MEDICINE REPORTS Overexpressed p32 localized in the endoplasmic reticulum and mitochondria negatively regulates calcium-dependent endothelial nitric oxide synthase activity
  • 2021년 혈관생물학, 신호전달, 면역생화학 MOLECULAR MEDICINE REPORTS Transient forebrain ischemia under hyperthermic condition accelerates memory impairment and neuronal death in the gerbil hippocampus by increasing NMDAR1 expression
  • 2018년 혈관생물학, 신호전달, 면역생화학 Cellular Signalling Tetraspanin CD82 represses Sp1-mediated Snail expression and the resultant E-cadherin expression interrupts nuclear signaling of beta-catenin by increasing its membrane localization
  • 2021년 혈관생물학, 신호전달, 면역생화학 Journal of Cellular Physiology Macrophage inhibitory cytokine-1 promotes angiogenesis by eliciting the GFRAL-mediated endothelial cell signaling
  • 2018년 혈관생물학, 신호전달, 면역생화학 Journal of Medicinal Chemistry Novel Hypoxia-Inducible Factor 1 alpha (HIF-1 alpha) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy
  • 2019년 혈관생물학, 신호전달, 면역생화학 Biomolecules & Therapeutics Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway
  • 2018년 혈관생물학, 신호전달, 면역생화학 Journal of Clinical Laboratory Analysis Delta neutrophil index: A reliable marker to differentiate perforated appendicitis from non-perforated appendicitis in the elderly
  • 2019년 혈관생물학, 신호전달, 면역생화학 CELLS A 2-Min Transient Ischemia Confers Cerebral Ischemic Tolerance in Non-Obese Gerbils, but Results in Neuronal Death in Obese Gerbils by Increasing Abnormal mTOR Activation-Mediated Oxidative Stress and Neuroinflammation
  • 2020년 혈관생물학, 신호전달, 면역생화학 CELLS p32-Dependent p38 MAPK Activation by Arginase II Downregulation Contributes to Endothelial Nitric Oxide Synthase Activation in HUVECs
  • 2020년 혈관생물학, 신호전달, 면역생화학 CELLS Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia
  • 2021년 혈관생물학, 신호전달, 면역생화학 FRONTIERS IN CARDIOVASCULAR MEDICINE Regulation of Endothelial and Vascular Functions by Carbon Monoxide via Crosstalk With Nitric Oxide
  • 2018년 혈관생물학, 신호전달, 면역생화학 METABOLIC BRAIN DISEASE Brain ischemic preconditioning protects against moderate, not severe, transient global cerebral ischemic injury
  • 2018년 혈관생물학, 신호전달, 면역생화학 METABOLIC BRAIN DISEASE Neuronal loss and gliosis in the rat striatum subjected to 15 and 30 minutes of middle cerebral artery occlusion
  • 2019년 혈관생물학, 신호전달, 면역생화학 METABOLIC BRAIN DISEASE Differential regional infarction, neuronal loss and gliosis in the gerbil cerebral hemisphere following 30 min of unilateral common carotid artery occlusion
  • 2018년 혈관생물학, 신호전달, 면역생화학 Molecular Immunology Activated human B cells stimulate COX-2 expression in follicular dendritic cell-like cells via TNF-alpha
  • 2020년 혈관생물학, 신호전달, 면역생화학 Biochemical Pharmacology Anti-metastatic effect of midazolam on melanoma B16F10 cells in the lungs of diabetic mice
  • 2018년 혈관생물학, 신호전달, 면역생화학 Analytical Biochemistry High-throughput investigation of transglutaminase 2 kinase regulation using a novel cysteine-modified peptide array
  • 2021년 혈관생물학, 신호전달, 면역생화학 FRONTIERS IN IMMUNOLOGY CU06-1004-Induced Vascular Normalization Improves Immunotherapy by Modulating Tumor Microenvironment via Cytotoxic T Cells
  • 2019년 혈관생물학, 신호전달, 면역생화학 The Prostate The metastasis suppressor CD82/KAI1 represses the TGF-β 1 and Wnt signalings inducing epithelial-to-mesenchymal transition linked to invasiveness of prostate cancer cells.
  • 2018년 혈관생물학, 신호전달, 면역생화학 JOURNAL OF THE AMERICAN HEART ASSOCIATION Arginase II Contributes to the Ca2+/CaMKII/eNOS Axis by Regulating Ca2+ Concentration Between the Cytosol and Mitochondria in a p32-Dependent Manner
  • 2021년 혈관생물학, 신호전달, 면역생화학 EXPERIMENTAL AND THERAPEUTIC MEDICINE Experimental pretreatment with YES-10(R), a plant extract rich in scutellarin and chlorogenic acid, protects hippocampal neurons from ischemia/reperfusion injury via antioxidant role
  • 2018년 혈관생물학, 신호전달, 면역생화학 JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE Early IV-injected human dermis-derived mesenchymal stem cells after transient global cerebral ischemia do not pass through damaged blood-brain barrier
  • 2018년 혈관생물학, 신호전달, 면역생화학 FASEB Journal REDD-1 aggravates endotoxin-induced inflammation via atypical NF-kappaB activation
  • 2018년 혈관생물학, 신호전달, 면역생화학 FASEB Journal The benzodiazepine anesthetic midazolam prevents hyperglycemia-induced microvascular leakage in the retinas of diabetic mice
  • 2019년 혈관생물학, 신호전달, 면역생화학 FASEB Journal Proinsulin C-Peptide prevents hyperglycemia-induced vascular leakage and metastasis of melanoma cells in the lungs of diabetic mice.
  • 2019년 혈관생물학, 신호전달, 면역생화학 FASEB Journal The vicious cycle between transglutaminase 2 and reactive oxygen species in hyperglycemic memory?induced endothelial dysfunction
  • 2019년 혈관생물학, 신호전달, 면역생화학 FASEB Journal SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175
  • 2018년 혈관생물학, 신호전달, 면역생화학 Plos One Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca2+-dependent HIF-1 alpha/ERR alpha circuit
  • 2020년 혈관생물학, 신호전달, 면역생화학 NUTRIENTS Pycnogenol(R)Supplementation Attenuates Memory Deficits and Protects Hippocampal CA1 Pyramidal Neurons via Antioxidative Role in a Gerbil Model of Transient Forebrain Ischemia
  • 2019년 혈관생물학, 신호전달, 면역생화학 SCIENTIFIC REPORTS Down-regulation of cyclin-dependent kinase 5 attenuates p53-dependent apoptosis of hippocampal CA1 pyramidal neurons following transient cerebral ischemia
  • 2019년 혈관생물학, 신호전달, 면역생화학 BIOCHIP JOURNAL Array-based Investigation of Amino Acids Responsible for Regulation of Transamidase and Kinase Activities of Transglutaminase 2
  • 2020년 혈관생물학, 신호전달, 면역생화학 BMB REPORTS Co-administration of erythropoietin and iron complex improves late-phase liver regeneration
  • 2021년 혈관생물학, 신호전달, 면역생화학 BMB REPORTS Low-dose metronomic doxorubicin inhibits mobilization and differentiation of endothelial progenitor cells through REDD1-mediated VEGFR-2 downregulation
  • 2020년 혈관생물학, 신호전달, 면역생화학 FRONTIERS IN PHARMACOLOGY CU06-1004 Alleviates Experimental Colitis by Modulating Colonic Vessel Dysfunction
  • 2021년 혈관생물학, 신호전달, 면역생화학 FRONTIERS IN PHARMACOLOGY Primaquine Diphosphate, a Known Antimalarial Drug, Blocks Vascular Leakage Acting Through Junction Stabilization
  • 2020년 혈관생물학, 신호전달, 면역생화학 Acta Biomaterialia Application of elastin-like biopolymer-conjugated C-peptide hydrogel for systemic long-term delivery against diabetic aortic dysfunction
  • 2019년 혈관생물학, 신호전달, 면역생화학 MACROMOLECULAR BIOSCIENCE Preventive Effects of Thermosensitive Biopolymer-Conjugated C-Peptide against High Glucose-Induced Endothelial Cell Dysfunction
  • 2020년 혈관생물학, 신호전달, 면역생화학 JOURNAL OF NEUROINFLAMMATION CLEC14A Deficiency Exacerbates Neuronal Loss by Increasing Blood-Brain Barrier Permeability and Inflammation
  • 2018년 혈관생물학, 신호전달, 면역생화학 Neurochemistry International Tumor necrosis factor receptor 2 is required for ischemic preconditioning-mediated neuroprotection in the hippocampus following a subsequent longer transient cerebral ischemia
  • 2018년 혈관생물학, 신호전달, 면역생화학 Neurochemistry International Chronic high-fat diet-induced obesity in gerbils increases pro-inflammatory cytokines and mTOR activation, and elicits neuronal death in the striatum following brief transient ischemia
  • 2020년 혈관생물학, 신호전달, 면역생화학 Molecules Experimental Pretreatment with Chlorogenic Acid Prevents Transient Ischemia-Induced Cognitive Decline and Neuronal Damage in the Hippocampus through Anti-Oxidative and Anti-Inflammatory Effects
  • 2019년 혈관생물학, 신호전달, 면역생화학 Molecular Pharmacology N-Terminal Modification of the Tetrapeptide Arg-Leu-Tyr-Glu, a Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Antagonist, Improves Antitumor Activity by Increasing its Stability against Serum Peptidases.
  • 2020년 혈관생물학, 신호전달, 면역생화학 Journal of Molecular Medicine CU06-1004 (endothelial dysfunction blocker) ameliorates astrocyte end-feet swelling by stabilizing endothelial cell junctions in cerebral ischemia/reperfusion injury
  • 2019년 혈관생물학, 신호전달, 면역생화학 Experimental Neurology Melatonin alleviates asphyxial cardiac arrest-induced cerebellar Purkinje cell death by attenuation of oxidative stress
  • 2020년 혈관생물학, 신호전달, 면역생화학 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Activity-expression profiling of glucose-6-phosphate dehydrogenase in tissues of normal and diabetic mice
  • 2019년 혈관생물학, 신호전달, 면역생화학 Life Sciences Insulin prevents pulmonary vascular leakage by inhibiting transglutaminase 2 in diabetic mice
  • 2018년 혈관생물학, 신호전달, 면역생화학 Journal of Biological Chemistry TNF-alpha elicits phenotypic and functional alterations of vascular smooth muscle cells by miR-155-5p-dependent down-regulation of cGMP-dependent kinase 1
  • 2021년 혈관생물학, 신호전달, 면역생화학 JOURNAL OF GINSENG RESEARCH Korean Red ginseng prevents endothelial senescence by downregulating the HO-1/NF-kappa B/miRNA-155-5p/eNOS pathway
  • 2018년 혈관생물학, 신호전달, 면역생화학 JOURNAL OF BIOLOGICAL CHEMISTRY NF-κB-Responsive miRNA-31-5p elicits endothelial dysfunction associated with preeclampsiavia downregulation of endothelial nitric oxide synthase
  • 2021년 혈관생물학, 신호전달, 면역생화학 ANTIOXIDANTS Neuroprotective Effects of Salicin in a Gerbil Model of Transient Forebrain Ischemia by Attenuating Oxidative Stress and Activating PI3K/Akt/GSK3 beta Pathway
  • 2018년 혈관생물학, 신호전달, 면역생화학 MOLECULAR ONCOLOGY Inhibition of VEGF-dependent angiogenesis and tumor angiogenesis by an optimized antibody targeting CLEC14a
  • 2022년 혈관생물학, 신호전달, 면역생화학 Cardiovascular Research Arginase II protein regulates Parkin-dependent p32 degradation that contributes to Ca2+-dependent eNOS activation in endothelial cells
  • 2018년 혈관생물학, 신호전달, 면역생화학 Chemico-Biological Interactions Melatonin attenuates scopolamine-induced cognitive impairment via protecting against demyelination through BDNF-TrkB signaling in the mouse dentate gyrus
  • 2018년 혈관생물학, 신호전달, 면역생화학 Chemico-Biological Interactions Rufinamide, an antiepileptic drug, improves cognition and increases neurogenesis in the aged gerbil hippocampal dentate gyrus via increasing expressions of IGF-1, IGF-1R and p-CREB
  • 2018년 혈관생물학, 신호전달, 면역생화학 ACS CHEMICAL NEUROSCIENCE Melatonin Improves Cognitive Deficits via Restoration of Cholinergic Dysfunction in a Mouse Model of Scopolamine-Induced Amnesia
  • 2018년 혈관생물학, 신호전달, 면역생화학 Experimental Gerontology Long-term treadmill exercise improves memory impairment through restoration of decreased synaptic adhesion molecule 1/2/3 induced by transient cerebral ischemia in the aged gerbil hippocampus
  • 2018년 혈관생물학, 신호전달, 면역생화학 EXPERIMENTAL AND MOLECULAR MEDICINE Arginase II inhibition prevents interleukin-8 production through regulation of p38 MAPK phosphorylation activated by loss of mitochondrial membrane potential in nLDL-stimulated hAoSMCs
  • 2019년 혈관생물학, 신호전달, 면역생화학 EXPERIMENTAL AND MOLECULAR MEDICINE NF-κB-responsive miR-155 induces functional impairment of vascular smooth muscle cells by downregulating soluble guanylyl cyclase
  • 2019년 혈관생물학, 신호전달, 면역생화학 EXPERIMENTAL AND MOLECULAR MEDICINE Arginase II activity regulates cytosolic Ca2+ level in a p32-dependent manner that contributes to Ca2+-dependent vasoconstriction in native low-density lipoprotein-stimulated vascular smooth muscle cells.
  • 2019년 혈관생물학, 신호전달, 면역생화학 EXPERIMENTAL AND MOLECULAR MEDICINE MicroRNA-148a/b-3p regulates angiogenesis by targeting neuropilin-1 in endothelial cells.
  • 2020년 혈관생물학, 신호전달, 면역생화학 EXPERIMENTAL AND MOLECULAR MEDICINE NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function
  • 2021년 혈관생물학, 신호전달, 면역생화학 EXPERIMENTAL AND MOLECULAR MEDICINE REDD1 is a determinant of low-dose metronomic doxorubicin-elicited endothelial cell dysfunction through downregulation of VEGFR-2/3 expressionRED1 is a determinant of low-dose metronomic doxorubicin-elicited endothelial cell dysfunction through downregula
  • 2018년 혈관생물학, 신호전달, 면역생화학 Biomedicine & Pharmacotherapy Melatonin improves vascular cognitive impairment induced by ischemic stroke by remyelination via activation of ERK1/2 signaling and restoration of glutamatergic synapses in the gerbil hippocampus
  • 2019년 혈관생물학, 신호전달, 면역생화학 Biomedicine & Pharmacotherapy Pretreated fucoidan confers neuroprotection against transient global cerebral ischemic injury in the gerbil hippocampal CA1 area via reducing of glial cell activation and oxidative stress
  • 2020년 혈관생물학, 신호전달, 면역생화학 Biomedicine & Pharmacotherapy Post-treatment With Oxcarbazepine Confers Potent Neuroprotection Against Transient Global Cerebral Ischemic Injury by Activating Nrf2 Defense Pathway
  • 2021년 혈관생물학, 신호전달, 면역생화학 Biomedicine & Pharmacotherapy Human plasminogen-derived N-acetyl-Arg-Leu-Tyr-Glu antagonizes VEGFR-2 to prevent blood-retinal barrier breakdown in diabetic mice
  • 2019년 혈관생물학, 신호전달, 면역생화학 ARCHIVES OF PHARMACAL RESEARCH Tumor endothelial cells as a potential target of metronomic chemotherapy
  • 2018년 혈관생물학, 신호전달, 면역생화학 Analytica Chimica Acta On-chip dual enzyme activity assay to investigate regulation of the transamidase and kinase activities of transglutaminase 2